Toxicity in animal models
A complete toxicity experiment will be proposed:
- Acute toxicity in mice, animals;
- Sub-acute toxicity in animals;
- Chronic toxicity in animals;
- “Abnormal Toxicity” in two animal species according to European guidelines;
- Monitoring: animal body weight, behavior, eventual death;
- Hematological and biochemical analysis;
- Macroscopic observation and histological analysis on main organs.
Histological analysis: microtom (Thermo Fisher)
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